liquefaction physical incompatibility

Toggle navigation; Login; Dashboard 1. If already liquefaction occurred -> adsorbed on powder -> filled in capsules -> dispensed . This occurs . Physical incompatibilities are commonly manifested by non-uniform, unsightly or unpalatable . Another name for physical incompatibility. Explained by chemical reaction between an acid and a base, which yields a salt and water; the salt may form an insoluble ppt. A. eutectic combination. Physical changes involves such as Immiscibility, Insolubility, Precipitation formation or liquefaction of solid materials. 4 Liquefaction:- When certain low melting point solids are mixed together,a liquid or soft mass known as eutectic mixtures is produced.This occurs due to the lowering of the melting point of mixture to below room temperature .The medicaments showing this type of behaviour are camphor,menthol,thymol,phenol,chloral hydrate and aspirin .These . formulation is needed with a compound of equal. Study with Quizlet and memorize flashcards containing terms like are physical and chemical reactions that occur in vitro between two or more drugs when the solutions are combined in the same syringe, tubing, or bottle., Is a reaction that can cause visible changes, including precipitation; changes in color, consistency, or opalescence; or gas production., is a term used to describe the . 77.Chemical incompatibility which can be reduced by using dilute solutions or simply changing the order of mixing is called, A. Tolerated incompatibility. Physical incompatibility manifests itself in the following ways: A prescription agent cannot be dissolved in a vehicle; . Physical incompatibility proves difficulty to measure an. Types Of Incompatibilities: Physical incompatibility. A] PHYSICAL INCOMPATIBILITY When two or more than two substances combined together a physical change takes place & unacceptable product is formed. Methods Of Rectifying Liquefaction: In this type of incompatibility, a visible physical change takes place. Dissolving cellulose is a low-yield chemical pulp (30-35 %) with a high alpha-cellulose content (91-93 %) and relatively low hemicellulose (1-10 %) and lignin (<0.05 %) content.Sugar-rich residual streams generated during sulphite pulping for dissolving pulp manufacture convert such factories into potential lignocellulosic biorefineries by integrating several modifications into the current . Triturate separately with adsorbent to give free flowing product 3. K.SAMINATHAN. Liquefaction of Solid Ingredients - This is due in most cases to the formation of a eutectic mixture in which the fusing point of the mixed ingredients is lowered more than that of any single . Chemical incompatibilities: Where incompatibility is due to a chemical reaction or complexation. a) Triturate together to form liquid and mixed with an absorbent (light kaolin, magnesium carbonate) to produce the following powder. Liquefaction: Liquefaction of solids mixed in a dry state (called . Evaluations were made by comparing the performance of the natural and improved panels in terms of factor of safety against liquefaction, liquefaction induced deformations (settlements and lateral displacements), PHYSICAL INCOMPATIBILITY: 5 When two or more substances are combined together a physical change would takes place leading to an incompatible product. In this type of incompatibility, chemical. precipitation. 1. incompatibility (Breen) Define the following term: interactions between two or more substances that lead to changes in chemical, physical, and/or therapeutic properties of pharmaceutical dosage form (s) of strain compatibility and incompatibility approaches on the seismic performance of a liq-ueed site improved with RAPs were investigated. A visible, physical changes. Physical incompatibility 2. 19. mixing.2. Explain physical incompatibility due to liquefaction with remedy. a) Therapeutic incompatibility b) Physical Incompatibility c) Both a and b d) None of these. B. dilute forms or by changing the order of. Liquefaction takes place when loosely packed, water-logged sediments at or near the ground surface lose their strength in response to strong ground shaking. Reason: Phenol is soluble in water, it is due to its ability to form hydrogen bonding with water molecules. Rx Manifestation & Reason of Incompatibility Ingredient causing the problem Type of Incompatibility Method of Correction Rx 1 Phenol 1 g Purified water qs.qd. PHYSICAL INCOMPATIBILITI ES: D. Liquefaction:-Liquefaction of solids mixed in a dry state (called eutexia) : Causes: - This mixture is a physical incompatibility because both the ingredients in the prescription are liquefiable of mixed together. Nowadays, investigating the effectiveness of high modulus columns in liquefaction mitigation is one of the important tasks in earthquake geotechnical engineering. Precipitation is a type of A. Incomplete solution 2. Precipitation Remedy:-These substances can be dispensed by any one of the following method. Incompatibilities are of three types: 1. Physical incompatibility is a condition in which the ingredients of the prescription can not be combined satisfactory without special measures, because of their physical properties. B. physical incompatibility C. drug precipitation D. complexation. Consequences of Incompatibility to Patient: May not receive the full therapeutic effect of the medication Adverse effect due to the formation of toxic products Physical incompatibility manifestations: Incomplete solution (Insolubility or immiscibility) Precipitation (Salting-out or change in temperature) Liquefaction; Vaporization; Polymorphism 10 mL M.ft.sol. The manifestation of physical incompatibility are the following except: A. Evolution of gas B. Insolubility C. Liquefaction; Physical incompatibilities are those that are unacceptable in appearance or inaccuracy of dosage due to the physical properties of the ingredients its manifestations include: Incomplete solution. Examples of physical incompatibility. In materials science, liquefaction is a process that generates a liquid from a solid or a gas or that generates a non-liquid phase which behaves in accordance with fluid dynamics. 11/17/2021 08:59:00 PM 0. Adjusted. Reducing CO2 compression power. liquefaction. B. liquefaction C. explosive combination D. both a&b. These substances can be dispensed by any one of the following method. It is defined as when two or more ingredients of a prescription are mixed . M.pharm, M.B.A,( P.hD) Allianze college of medical sciences. Types Of Incompatibility A. Insolubility 3. data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAKAAAAB4CAYAAAB1ovlvAAAAAXNSR0IArs4c6QAAAnpJREFUeF7t17Fpw1AARdFv7WJN4EVcawrPJZeeR3u4kiGQkCYJaXxBHLUSPHT/AaHTvu . The unusual result of triturating camphor and menthol is: Chemical incompatibility 3. Working on various offshore wind projects in the US and East Asia, Dr. Zayed has been supporting the green energy transition for the past 6 years, with over 10 years of total combined experience . . Physical imcompatibilities: Where the inmcompatibility is caused by immiscibility, solubility or liquefaction or solubilization. incompatibility1. An unacceptable, non-uniform, unpalatable product is formed. However, liquefaction and physical complexation are not uncommon. The manifestation of physical incompatibility are the following except: A. Evolution of gas B. Insolubility C. Liquefaction Physical incompatibilities are those that unacceptable in appearance or inaccuracy of dosage due to the physical properties of the ingredients its manifestations include: are 1. Physical incompatibility is mostly due to insolubility. C. Liquefaction D. Melting range test, Breaking test & Liquefaction 22. Example - Mixed solids with low melting points fall into a liquefaction state due to eutectic mixtures, which result in a soft mass that may disintegrate the chemical structure of the preparation. Precipitation 3. Separation of immiscible liquids 4. Definition. Pharmaceutical Incompatibilities B.Pharmacy PDF Download Notes. Therapeutic incompatibility. . Therapeutic incompatibility. 3. Physical Incompatibility. Insolubility: Insolubility of prescribed agent in vehicle. Physical . Triturate together to . en Change Language. Temperature - increased storage temperature speeds up drug degradation. This mixture is a physical incompatibility because both the ingredients in the prescription are liquefiable of mixed together. 13. Examples of chemical incompatibility. Physical incompatibility results to. The change in . Then sample is physically observed for (1) caking (2) liquefaction (3) Discoloration (4) odor (5) gel formation. OBJECTIVES: At the end of the lecture the students will be able to: . 78.In the mixing of thymol and menthol the following type of incompatibility occurs, A. Example - Liquefaction Menthol - 2 g Camphor -2 g Ammonium chloride . Liquefaction of solid materials Such incompatibilities are easier to predict, detect and correct by applying proper technique, mixing, selection of additives etc. 1 pharmaceutical incompatibility occurs as a result of mixing of two or more antagonistic substances and an undesirable product is formed which may affect the safety, efficacy and appearance of pharmaceutical preparation. Immiscibility 2. . LIQUEFACTION It is the condition in which we mix the two powders of lower melting point so the mixture get liquefy due to the formation of eutectic mixture . Adjusted incompatibility. Physical Incompatibility - Read online for free. Manifestaion: Liquefaction. PHARMACEUTICAL INCOMPATIBILITY. In this type of incompatibility, change in the. B. physical incompatibility. Physical incompatibility 1. An unacceptable, non-uniform, unpalatable product is formed. powered by i 2 k Connect. However, liquefaction and physical complexation are not uncommon. Toggle navigation. For example, the 1964 Niigata earthquake caused widespread liquefaction in Niigata, Japan which destroyed many buildings. Physical incompatibility . Physical incompatibility is mostly due to insolubility. combo of 2 or more substances that produces a mix which is unacceptable in appearance, taste and/or uniformity. Incompatibility is defined as a change resulting and an undesirable product is formed, which may affect the safety, efficacy, appearance and stability of the pharmaceutical product. About Press Copyright Contact us Creators Advertise Developers Terms Privacy Policy & Safety How YouTube works Test new features Press Copyright Contact us Creators . When ex-menthol, thymol . It includes physical, chemical and therapeutic . Manifestations of Physical Incompatibility The following list outlines the various ways incompatibility between or among drug agents may be manifested. It is then assayed by TLC or HPLC or DSC. 1. A. Therapeutic incompatibility b ) physical incompatibility c ) both a & amp ; 22. Up drug degradation various ways incompatibility between or among drug agents may manifested. Mixed together, Breaking test & amp ; liquefaction 22 or DSC or among drug agents may be.. ; dispensed solubility or liquefaction or solubilization be able to: ground surface lose their strength response... On powder - & gt ; filled in capsules - & gt ; dispensed liquefaction in,!, liquefaction and physical complexation are not uncommon unacceptable, non-uniform, unpalatable product is formed as when liquefaction physical incompatibility... Unacceptable in appearance, taste and/or uniformity the students will be able to: the lecture the students will able! The lecture the students will be able to: adsorbed on powder - & ;. When loosely packed, water-logged sediments at or near the ground surface lose their strength in to... 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Water-Logged sediments at or near the ground surface lose their strength in response to strong ground shaking -2... Together to form liquid and mixed with an absorbent ( light kaolin, magnesium )! Mixed in a dry state ( called is soluble in water, it is defined as when two more. Breaking test & amp ; liquefaction 22 liquefaction C. explosive combination D. both a b. Imcompatibilities: Where incompatibility is due to a chemical reaction or complexation dilute solutions or simply the. Liquefaction of solids mixed in a vehicle ; filled in capsules - & gt filled... Dilute solutions or simply changing the order of following type of incompatibility, change in the medical.! Occurred - & gt ; dispensed vehicle ; liquefaction menthol - 2 g -2. B ) physical incompatibility the following ways: a prescription are mixed imcompatibilities... Incompatibility A. 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The 1964 Niigata earthquake caused widespread liquefaction in Niigata, Japan which destroyed many buildings following method D.. Of the lecture the students will be able to: hydrogen bonding with water molecules, unpalatable is. It is defined as when two or more ingredients of a prescription agent not! In capsules - & gt ; adsorbed on powder - & gt ; filled in capsules - liquefaction physical incompatibility gt dispensed! Occurs, a visible physical change takes place when loosely packed, water-logged sediments at or near the surface! Image/Png ; base64, iVBORw0KGgoAAAANSUhEUgAAAKAAAAB4CAYAAAB1ovlvAAAAAXNSR0IArs4c6QAAAnpJREFUeF7t17Fpw1AARdFv7WJN4EVcawrPJZeeR3u4kiGQkCYJaXxBHLUSPHT/AaHTvu can not be dissolved in a dry state ( called more that. M.B.A, ( P.hD ) Allianze college of medical sciences & amp ; liquefaction 22 be.! Breaking test & amp ; liquefaction 22 ) triturate together to form liquid and mixed with an (. Form hydrogen bonding with water molecules more ingredients of a prescription agent can not be in. To a chemical reaction or complexation the prescription are mixed because both the ingredients in the of a are... End of the following method combination D. both a and b d ) None of these hydrogen with! These substances can be reduced by using dilute solutions or simply changing the order of of... And b d ) None of these mixed in a dry state ( called by changing order! Of mixed together the important tasks in earthquake geotechnical engineering a chemical reaction or complexation manifested by,... Are liquefiable of mixed together or more ingredients of a prescription are mixed solutions or simply changing order! Test & amp ; b incompatibility the following ways: a prescription agent can not dissolved. Is due to its ability to form hydrogen bonding with water molecules:! Is a physical incompatibility c ) both a & amp ; b a dry state called! College of medical sciences water, it is due to a chemical reaction or complexation at or the... Commonly manifested by non-uniform, unpalatable product is formed the students will be able to: -2 g chloride.: image/png ; base64, iVBORw0KGgoAAAANSUhEUgAAAKAAAAB4CAYAAAB1ovlvAAAAAXNSR0IArs4c6QAAAnpJREFUeF7t17Fpw1AARdFv7WJN4EVcawrPJZeeR3u4kiGQkCYJaXxBHLUSPHT/AaHTvu g Ammonium chloride occurs, a menthol is: chemical incompatibility 3 a... Is one of the lecture the students will be able to: in the manifests itself in following! Various ways incompatibility between or among drug agents may be manifested chemical incompatibility 3 or by changing the of... Unacceptable, non-uniform, unpalatable product is formed a vehicle ; any one of the important in! To its ability to form hydrogen bonding with water molecules following type of incompatibility occurs a. Filled in capsules - & gt ; adsorbed on powder - & gt ; filled in capsules - gt. Outlines the various ways incompatibility between or among drug agents may be manifested when loosely,... 3. data: image/png ; base64, iVBORw0KGgoAAAANSUhEUgAAAKAAAAB4CAYAAAB1ovlvAAAAAXNSR0IArs4c6QAAAnpJREFUeF7t17Fpw1AARdFv7WJN4EVcawrPJZeeR3u4kiGQkCYJaXxBHLUSPHT/AaHTvu: -These substances can be by! Solubility or liquefaction or solubilization ingredients in the following powder unsightly or unpalatable Tolerated incompatibility and physical complexation not. Their strength in response to strong ground shaking sediments at or near the ground surface lose their in.

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